TY - JOUR T1 - Antimicrobial Activities of Diallyl Disulfide Against Fish Pathogenic Bacteria AU - Shin, Gee-Wook AU - Heo, Gang-Joon AU - Hwang, Soon-Ho AU - Park, Se-Chang AU - De Zoysa, Mahanama JO - Journal of Animal and Veterinary Advances VL - 11 IS - 13 SP - 2280 EP - 2283 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.2280.2283 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.2280.2283 KW - Diallyl disulfide KW -fish pathogenic bacteria KW -antimicrobial activity KW -aquaculture KW -disk KW -diffusion test AB - As a major pathogen for fish, the antimicrobial activity of Diallyl Disulfide (DADS) was examined for the following bacteria, Aeromonas hydrophila, A. salmonicida ssp. masoucida, A. salmonicida ssp. salmonicida, Edwardsiella tarda, Vibrio vulnificus, V. paraheamolyticus and L. anguillarum. About 10 ug mL-1 and more of DADS formed a clear inhibitory zone to all pathogenic bacteria in a disk diffusion test. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values were in the ranges of 160-640 and 640-1280 ug mL-1 of DDS, respectively. The most sensitive pathogen to DDA was V. vulnificus (160 ug mL-1 for MIC and 640 ug mL-1 for MBC) followed by E. tarda (320 ug mL-1 for MIC and 640 ug mL-1 for MBC). These results suggest bioavailability of DADS for controlling bacterial pathogens in aquaculture. ER -