TY - JOUR
T1 - A Novel Method Based on Ligase Detection Reaction for PGC-1α G646A Gene Polymorphism and its Genetic Effect on Meat Quality in Chicken
AU - Hui-Fang, Li AU - Kuan-Wei, Chen AU - Ying, Zang AU - Yan-Ju, Shan AU - Wen-Juan, Xu AU - Jing-Ting, Shu
JO - Journal of Animal and Veterinary Advances
VL - 10
IS - 22
SP - 2921
EP - 2925
PY - 2011
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2011.2921.2925
UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.2921.2925
KW - China
KW -PGC-1a gene
KW -ligase detection reaction
KW -chicken
KW -polymorphism
KW -meat quality
AB - The Peroxisome Proliferators-activated receptor-γ Coactivator-1α (PGC-1α) was investigated as a candidate gene for meat quality and fatness traits in chicken because of its prominent role in muscle fiber specialization and adipogenesis. Variations of PGC-1α+646G/A may associate with chicken meat quality traits. The objective of the current research was to investigate the association of this single nucleotide polymorphisms in PGC-1α gene with meat quality traits in Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by Polymerase Chain Reaction-Ligation Detection Reaction (PCR-LDR) Method. Marker-trait association analysis indicated that there were significant associations between G646A genotypes and the trait of water loss rate. Researchers putatively drew the conclusion that this SNP in PGC-1α gene could be used as the potential molecular marker for meat quality trait in chicken.
ER -