TY  - JOUR
T1  - The RAB38-Hosted Chicken <I>Mir-1657</I> Gene: Sequence Conservation, Seed Region Polymorphisms and Putative Targets
AU - Zhang, Chuan-Sheng AU - Geng, Li-Ying AU - , Yang-Qing AU - Zhu, Wen-Jin AU - Wang, Qiu-Yue AU - Zhang, Xiang-Zhai AU - Sun, Hong-Nuan AU - Li, Xiao-Song AU - Liu, Rui-Zao AU - Liu, Xiao-Hui 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 18
SP  - 2343
EP  - 2348
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.2343.2348
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.2343.2348
KW  - biological
KW  -functional annotation
KW  -chicken
KW  -SNP
KW  -Gga-mir-1657
KW  -China
AB  - The aim of this study was first to investigate the evolutionary conservatism of mir-1657 among in different species and then to investigated a G-A polymorphism in the seed region of mature gga-mir-1657 sequence with forced PCR-RFLP using Ava III nuclease in six chicken populations; 178 individuals from Beijing Fatty chicken (BF), Wenshangluhua chicken (WL), Jiningbairi chicken (JB), Siyuwugu chicken (WG) and Langya chicken (LY) breeds. Bioinformatics analyses indicated that <I>gga-mir-1657</I> gene G&gt;A polymorphism may alter target selection and secondary structure. The findings indicate that the rs14934924 SNP may exert profound biological effects in the formation of some special phenotype of chicken and enables functional annotation of gga-mir-1657.
ER  -