TY - JOUR
T1 - Expression Profiling of MYOZ1 Gene in Porcine Tissue and C2C12 Cells
AU - Cao, Jian-Hua AU - Li, Xin-Yun AU - Zhao, Shu-Hong AU - Zhou, Ke AU - Liu, Yin
JO - Journal of Animal and Veterinary Advances
VL - 10
IS - 15
SP - 1917
EP - 1921
PY - 2011
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2011.1917.1921
UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.1917.1921
KW - adult
KW -expression profiling
KW -skeletal
KW -C2C12 cells
KW -porcine
KW -Myozenin-1 (MYOZ1)
KW -tissue
AB - The structure and function of Z-discs were related strongly
to the normal physiological phenotype and function of skeletal muscle. The protein
Myozenin (MYOZ), an α-actinin and γ-filamin-binding Z-disc globular
protein expressed predominantly in skeletal muscle was possibly involved in
the confirmation and function of Z-discs. Here we described MYOZ1 gene
which has a significantly higher expression level in skeletal muscle than several
other tissues in porcine. Furthermore, MYOZ1 transcripts in three porcine development
stages (embryonic 33 days, embryonic 65 days and adult) of skeletal muscle shown
stepwise increasingly expression pattern by using quantitative PCR analysis.
Functional assays were conducted using C2C12 cells and the results implied MYOZ1
was not involved in both of cellular proliferation and differentiation.
ER -