TY - JOUR T1 - Expression Profiling of MYOZ1 Gene in Porcine Tissue and C2C12 Cells AU - Cao, Jian-Hua AU - Li, Xin-Yun AU - Zhao, Shu-Hong AU - Zhou, Ke AU - Liu, Yin JO - Journal of Animal and Veterinary Advances VL - 10 IS - 15 SP - 1917 EP - 1921 PY - 2011 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2011.1917.1921 UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.1917.1921 KW - adult KW -expression profiling KW -skeletal KW -C2C12 cells KW -porcine KW -Myozenin-1 (MYOZ1) KW -tissue AB - The structure and function of Z-discs were related strongly to the normal physiological phenotype and function of skeletal muscle. The protein Myozenin (MYOZ), an α-actinin and γ-filamin-binding Z-disc globular protein expressed predominantly in skeletal muscle was possibly involved in the confirmation and function of Z-discs. Here we described MYOZ1 gene which has a significantly higher expression level in skeletal muscle than several other tissues in porcine. Furthermore, MYOZ1 transcripts in three porcine development stages (embryonic 33 days, embryonic 65 days and adult) of skeletal muscle shown stepwise increasingly expression pattern by using quantitative PCR analysis. Functional assays were conducted using C2C12 cells and the results implied MYOZ1 was not involved in both of cellular proliferation and differentiation. ER -