TY  - JOUR
T1  - Effects of ATP Citrate Lyase and Adipose Differentiation-Related Protein<I> </I>Gene Polymorphisms on Adipose Deposition and Meat Quality Traits in Pigs
AU - Jiang, Si-Wen AU - Deng, Chang-Yan AU - Xiong, Yuan-Zhu AU - Ren, Zhu-Qing 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 12
SP  - 1610
EP  - 1615
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.1610.1615
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.1610.1615
KW  - ACL
KW  -pigs
KW  -polymorphism
KW  -ADRP
KW  -association analysis
KW  -China
AB  - Adipose genes are potential candidates for meat quality. In the present study, two ESTs, coding for ATP-Citrate Lyase (ACL) and Adipose Differentiation-Related Protein (<I>ADRP</I>) gene were isolated via mRNA differential display technique. A C/T SNP in the 5&#146;-flanking region of<I> ACL </I>gene and an insertion/deletion mutation in the fourth intron of <I>ADRP</I> gene were found, respectively. The selected pigs were genotyped at porcine ACL XhoI-RFLP and ADRPinsertion/deletion mutation. The results showed that the ACL genotypes presented a significant effect on leaf fat weight (p&lt;0.01), caul fat weight (p&lt;0.05), pH (LD) (p&lt;0.01) and water holding capacity (p&lt;0.05). Moreover, this site seemed to be significantly dominant in action (p&lt;0.01 for leaf fat weight, caul fat weight and pH (LD); p&lt;0.05 for water holding capacity) and allele B was associated with increase of both leaf and caul fat weights whereas with decrease of meat pH of Longissimus Dorsi and water holding capacity. The ADRP genotypes showed significance both on leaf fat weight and water moisture (p&lt;0.05). The additive effects were significant for these traits while allele D increased the traits' phenotypic values. Based on this research, we proposed that both of two loci were potential makers for adipose deposition and meat quality traits.
ER  -