TY - JOUR T1 - Effects of Sildenafil on Dental Tissue AU - Dalli, Mehmet AU - Ince, Bayram AU - Gunay, Ahmet AU - Agacayak, Serkan Kamil AU - Alp, Harun AU - Atilgan, Serhat AU - Erol, Behcet AU - Soker, Sevda AU - Yaman, Ferhan JO - Journal of Animal and Veterinary Advances VL - 10 IS - 9 SP - 1124 EP - 1126 PY - 2011 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2011.1124.1126 UR - https://makhillpublications.co/view-article.php?doi=javaa.2011.1124.1126 KW - bone KW -tissue KW -experimental research KW -dental tissue KW -Sildenafil KW -dental pulp AB - To investigate the effects of Sildenafil on dental tissue. The study was performed with adult female Wistar-Albino rats. Control group (n = 7) were fed on standard laboratory diet until surgery. The study group (n = 7) were administered Sildenafil orally with orogastric tube 10 mg kg-1 once a day for 30 days. Each rat was anesthetized and mandibular bone with incisor teeth and soft tissue were removed. Dental pulp, dentin, periodental ligament, periodental soft tissue and bone were examined histologically. Neovascularization on the dental pulp and gingiva were significantly higher in the study group. Sildenafil can be used as a supporting factor in dental tissue healing. ER -