TY  - JOUR
T1  - Serum Proteins, Thyroid Hormones and Alkaline Phosphatase Concentrationsin Acute Experimental  <I>Trypanosoma congolense</I> Infection in <I>Yankasa</I> Sheep Immunomodulated with Levamisole
AU - , M. Bisalla AU - , K.A.N. Esievo AU - , N.D.G. Ibrahim AU - , I.A. Lawal 
JO  - Journal of Animal and Veterinary Advances
VL  - 6
IS  - 4
SP  - 586
EP  - 590
PY  - 2007
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2007.586.590
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2007.586.590
KW  - Trypanosoma congolense
KW  -Yankasa sheep
KW  -immunomodulation
KW  -serum proteins
KW  -thyroid hormones
KW  -alkaline phosphatase
AB  - Serum proteins, thyroid hormones and alkaline phosphatase concentrations were measured in <I>Yankasa</I> sheep experimentally infected with <I>T. congolense.</I> Parasitemia occurred in the <I>T. congolense</I> infected sheep immunomodulated with levamisole two days earlier than the infected group without immunodulation.Packed cell volume decreased significantly(p< 0.05) in the infected groups with and without immunomodulation when compared to the controls from the first week of infection up to the end of the experiment. Serum total protein, albumin, Thyroxine (T4) and Triiodothyronine (T3) decreased significantly (p< 0.05) in the infected sheep with and without immunodulation when compared to the controls. Serum Thyrotopin (TSH) and Alkaline Phosphate (AP) did not alter significantly (p>0.05) in the infected sheep with and without immunomodulation when compared to the controls throughout the period of the experiment. In general, levamisole administration did not appear to alter the infection when compared to the infected group without immunomodulation.
ER  -