TY  - JOUR
T1  - <I>Lactobacillus casei </I>DSPV 318T Capacity to Colonize and Remain in Mouse Gastrointestinal Tract
AU - , L.S. Frizzo AU - , M.V. Zbrun AU - , E. Bertozzi AU - , L.P. Soto AU - , G. Sequeira AU - , E. Marti AU - , R. Lajmanovich AU - , M.R. Rosmini 
JO  - Journal of Animal and Veterinary Advances
VL  - 6
IS  - 10
SP  - 1158
EP  - 1166
PY  - 2007
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2007.1158.1166
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2007.1158.1166
KW  - Intestinal tract
KW  -Lactobacillus
KW  -mice
KW  -probiotic
AB  - Probiotics are microbial cells that develop a beneficial effect on the host’s health while passing through the gastrointestinal tract. Their survival rate and persistence in the hosts are important factors when selected to be used like food supplements in animal farms. In the present study, the <I>Lactobacillus casei</I> DSPV 318T capacity to colonize and remain in the mouse gastrointestinal tract was studied. The inoculum was made of <I>Lactobacillus casei</I> DSPV  318T, <I>L. salivarius</I> DSPV  315T and <I>Pediococcus acidilactici</I> DSPV  006T, 3 lactic acid bacteria from bovine origin. The inoculum, with the 3  microorganisms suspended in a NaCl  0.15M solution, was orally administered to an experimental group of mice, by gavages in a 0.1 mL total volume, with a 10<SUP>9</SUP> CFU final concentration. One control group only received NaCl solution as placebo. <I>Lactobacillus casei</I> DSPV  318T showed a capacity to remain in a complex ecological niche, such as the mouse intestine, for a longer period of time than the one the treatment lasted. The inoculum administration did not produce any change in the individual activity or appearance, being this an indicator of both, the general state of health and the absence of adverse effects. Followed by doses every other day, the initial massive administration system was efficient considering that such microorganism lodged in the individuals’ intestine. The inoculum did not interfere with the normal functioning of the intestinal microbiota, resulting innocuous to the host.
ER  -