TY - JOUR T1 - Sedative and Anticonvulsant Properties of the Decoction of Balanites aegyptiaca (Balanitaceae) AU - , Elisabeth Ngo Bum AU - , Neteydji Sidiki AU - , Taiwe AU - , Paul Fasutin Seke Etet AU - , Frededic Maidawa AU - , Silvere Vincent Rakotonirina AU - , Alice Rakotonirina JO - Journal of Animal and Veterinary Advances VL - 4 IS - 1 SP - 34 EP - 38 PY - 2005 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2005.34.38 UR - https://makhillpublications.co/view-article.php?doi=javaa.2005.34.38 KW - AB - The decoction of Balanites aegyptiaca, a plant used in traditional medicine in Africa for many diseases, possesses anticonvulsant and sedative activity in mice. This decoction protected mice against strychnine- and pentylenetetrazol-induced seizures. But Balanites aegyptiaca decoction had no effect against picrotoxin-induced seizures. In the other side, the decoction of Balanites aegyptiaca potentiated sleep-induced by diazepam. The total sleep time of the control group was multiply by 4 in the presence of the decoction at a dose of 1000 mg /kg (from 12 to 59 min). With these effects, the decoction of Balanites aegyptiaca L. seem to posses sedative and anticonvulsant properties that might explain its use as a traditional medicine for epilepsy in Africa. ER -