@article{MAKHILLJAVA20201994641,
    title = {Potential Probiotics and Their Application},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {19},
    number = {9},
    pages = {117-123},
    year = {2020},
    issn = {1680-5593},
    doi = {javaa.2020.117.123},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2020.117.123},
    author = {Getachew and},
    keywords = {Health improvement,probiotics,risk,safety regulation,selection criteria},
    abstract = {Probiotics are health promoting viable
microorganisms which have useful effects on the health of
digestive system when acquired in a defined dosage.
Probiotics can be formulated in to different types of
products like food, drugs and dietary supplements.
Probiotics improve digestion of food, absorption of
nutrients, reducing cholesterol levels, pharmaceuticals
development, functional food development and preventing
growth of undesirable microorganisms in the digestive
tract. The selection of probiotics from different sources
involving the evaluation of the basic features of these
bacteria, including acid, salt and bile tolerance, ability to
adhere to the gut, combat pathogens in the GIT,
production of antimicrobial substances, ability to
stimulate the response and ability to influence the
metabolic activities. Potential probiotics has been isolated
from human sources such as feces of healthy adults,
breast fed infants and human breast milk and animal
sources are poultry, pigs and ruminants. Probiotic bacteria
isolated from these sources like <i>Enterococcus faecalis</i>,
<i>L. salivarius</i>, <i>L. rhamnosus</i> and <i>L. casei</i> helps to improve
human health particularly today with the increasing threat
of antibiotic over usage and the prevalence of antibiotic
resistance organisms. The use of growth promoting
antibiotics in animal feeds is banded in different countries
due to potential risks such as the spread of resistance
genes and the contamination of milk and meat with
antibiotic residues. As a result, many livestock producers
and researches have explored different alternative
strategies to enhance animal performance and health.
Probiotics are one of the best alternatives to improve
animal production. The use of probiotics in animals
improves milk production in lactating cows, milk fat, milk
protein and SNF contents. Safety is an overarching
concern among all probiotic stakeholders, from
government regulatory agencies, to consumer advocacy
organizations, to manufacturers. However, still there are
not systematic reviews that analyze adverse effects and
safety of probiotic administration evidence to date has
demonstrated no serious adverse effects. The market of
probiotics in global market is rapidly increased. The
market in 2015 was $33.19 billion and expected to reach
$46.55 billion by 2020 which indicates a compound
annual growth rate of 7%.}
    }