@article{MAKHILLJAVA20131264105,
title = {A Novel PCR-RFLP (Xba I) Polymorphism Analysis of the Bovine Calpastatin (CAST) Gene in Chinese Luxi Cattle},
journal = {Journal of Animal and Veterinary Advances},
volume = {12},
number = {6},
pages = {788-790},
year = {2013},
issn = {1680-5593},
doi = {javaa.2013.788.790},
url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2013.788.790},
author = {Dongying},
keywords = {Genetic polymorphisms,CAST gene,haplotype,RFLP,cattle},
abstract = {Calpastatin (CAST) is a specific inhibitor of the ubiquitous
calcium-dependent proteases-μ-calpain and m-calpain, found in mammalian
tissues. In the coding region of the bovine CAST gene (CAST) the new
nucleotide sequence polymorphism was found being a substitution G→C at position
962 nt (consensus sequence-GenBank AF281256). Consensus of bovine CAST sequence
with that of human revealed that G→C substitution was located at position 1460
nt of exon 12. Computer analysis of the mutation showed the Ser→Thr substitution
for CAST protein. The frequency of alleles C and G was 0.41 and 0.59, respectively.
The message from these results is that CAST gene may probably be considered
as a candidate marker for beef quality.}
}