@article{MAKHILLJAVA201211243909,
title = {Observation on Viral Variation and Vaccine Development in Mareks Disease in China},
journal = {Journal of Animal and Veterinary Advances},
volume = {11},
number = {24},
pages = {4611-4614},
year = {2012},
issn = {1680-5593},
doi = {javaa.2012.4611.4614},
url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.4611.4614},
author = {Zhenhua,Liping,Yonghao,Ping,Lijuan and},
keywords = {vaccine,viral variation,Marek`s disease,epidemic,evolution},
abstract = {Mareks Disease (MD) is one of the main infectious diseases
that threaten the healthy development of the Chinese poultry industry. The evolution
of epidemic strains of the MD Virus (MDV) in China is different from the evolution
of strains overseas. The meq gene sequence of pathogenic strains is different
from that of the attenuated vaccine strain (MDV-1). The meq and L-meq
gene sequences of the MDV in the lymphoid tissue of chickens in latency period
are homologous. The meq gene was only found in the lymphoid tissue of
chickens during the onset period.}
}