@article{MAKHILLJAVA201211193754,
    title = {VEGF/VEGFR-2 mRNA Expression in a Mouse Menstrual-Like Model by Pharmacologic Progesterone Withdrawal},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {19},
    pages = {3512-3516},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.3512.3516},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.3512.3516},
    author = {Xiangbo and},
    keywords = {Vascular Endothelial Growth Factor (VEGF),Vascular Endothelial Growth Factor Receptor 2 (VEGFR2),mouse menstrual-like model,pharmacologic progesterone withdrawal,epithelium},
    abstract = {Vascular Endothelial Growth Factor (VEGF)/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) are vital in menstruation. This study aimed to explore their expressions in a mouse menstrual-like model by pharmacologic progesterone withdrawal. A mouse model was prepared by administration of mifepristone after decidualization of ovariectomized mice. Semiquantive-PCR and <I>in situ</I> hybridization were performed to the expression patterns of VEGF/VEGFR-2 mRNA. VEGF mRNA peaked at 24 h and obviously reduced at other time points. VEGF mRNA was mainly located in the basal zone from 0-24 h, epithelium and stroma zone from 32-48 h. VEGFR-2 mRNA was higher at 0 and 40 h rather weak at 8, 16 and 32 h, nearly not expressed at 24 and 40 h. VEGFR-2 mRNA was strongly located in the basal zone at 0, 8 and 16 h in the epithelium zone at 24, 32 and 48 h and epithelium and stroma zone at 40 h. The locations of VEGF/VEGFR-2 in mouse menstrual-like model displayed regional character.}
    }