@article{MAKHILLJAVA20121133170,
    title = {Cloning and Sequence Analysis of Rabbit Interleukin-10 (<I>IL-10</I>) Gene Promoter},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {3},
    pages = {323-326},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.323.326},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.323.326},
    author = {Wu,He,Zhang,Feng,Wang,Pan,Wan and},
    keywords = {bioinformatics,transcription factor,promoter,IL-10,gene,China},
    abstract = {To clone the IL-10 promoter of rabbit and analyse its sequence, this study amplified the 5 flanking region of rabbit IL-10, compared the genomes and used bioinformatics software to make a forecast. Then, the researchers comfirmed partial promoter sequences and analysed some transcription factors of the <I>IL-10</I> gene promoter. The study showed that rabbit and human <I>IL-10</I> gene promoter had some similarities which all cotained GAGA, CAAT and TATA. The transcriptional start site started from -80 bp of translation initiation codon (ATG) upstream region. The promoter also had some transcription factors such as AP-1, Myogenin, c-Ets-1, C/EBP alpha and so on. Results of this study predicted partial sequences, transcriptional start site and some transcriptional regulating factors binding sites of <I>IL-10</I> gene promoter which would lay the foundation of lucubrating the expression and regulation of rabbit <I>IL-10</I> gene.}
    }