@article{MAKHILLJAVA201211103451,
    title = {Identification, Cloning, Expression of a Novel Functional <I>Anas platyrhynchos</I> mRNA TLR4},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {10},
    pages = {1727-1733},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.1727.1733},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.1727.1733},
    author = {Yu,Yongjun,Shanshan,Liancheng,Jisheng,Xiaokun,Wenyu,Changjiang,Reham R.,Wael K.,Mostafa,Mohamed and},
    keywords = {Anseriformes,Avian,duck-toll like receptor,TLR4,gene expression,China},
    abstract = {Toll like receptor mediate immune response through recognition of Pathogen-Associated Molecular Patterns (PAMPs) thus play important roles in host defense. Little is known about the Avian Immune System structure and the majority of it based on chicken as a Universal Avian Model while recent researches showed that a lot of factor not common between chicken and other birds. This research aimed to identify and clone the duck TLR4 as a model to Anseriformes species, researchers success to clone a novel functional dTLR4 mRNA and deposit into the NCBI GenBank database where the mRNA consist of 2529 nucleotide and it showed 81% identity with chicken and 78% identity with zebra finch while showed 95% identity with goose. The translated amino acid showed that the gene consist of 843 amino acid and the transmembrane structure analysis reveal a novel unique LRR motifs in duck and absent in both chicken and zebra finch at the position 56-80 also showed that TIR domain consist of 146 amino acid not 145 like chicken and zebra finch.}
    }