@article{MAKHILLJAVA20121173331, title = {Residue Depletion of Florfenicol and its Metabolite Florfenicol Amine in Eggs}, journal = {Journal of Animal and Veterinary Advances}, volume = {11}, number = {7}, pages = {1012-1017}, year = {2012}, issn = {1680-5593}, doi = {javaa.2012.1012.1017}, url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.1012.1017}, author = {Kaizhou,Huisheng,Longfei,Yuping,Xing,Yilin,Dong,Xuesheng,Guojun,Xiaojie,Yingying,Jinyu and}, keywords = {Florfenicol,florfenicol amine,residue depletion,eggs,yolk,yolk}, abstract = {Eggs of laying hens were used to study residue depletion of Florfenicol (FF) and its metabolite Florfenicol Amine (FFA) after oral dose (25.0, 50.0 and 100.0 mg kg-1 body weight), once daily for 5 days. The residues were determined by High Performance Liquid Chromatography with Fluorescence Detection (HPLC-FLD). The maximum concentration of FF was all detected at 1 day in the albumen, yolk and whole eggs; the maximum concentration of FFA was detected at 1 day in the albumen and whole eggs, at 3 days in the yolk after cessation of medication. After oral administration of 100.0 mg kg-1, concentrations of FF and FFA were all below the LODs (1.5 μg kg-1 for FF and 0.5 μg kg-1 for FFA) at 7 days for the albumen, 11 days for yolk and 10 days for whole egg after cessation of medication.} }