N. Three-Ost, R. Duangsong, P. Sithithaworn, C. Sota, The Effectiveness of Health Education Program for Liver Fluke Preventing Behavior by Using Hand book and VCD in Primary School Students, The Social Sciences, Volume 6,Issue 2, 2011, Pages 136-140, ISSN 1818-5800, sscience.2011.136.140, (https://makhillpublications.co/view-article.php?doi=sscience.2011.136.140) Abstract: This quasi experimental research aimed to study the effectiveness of health education program by using handbook and VCD for liver fluke prevention. Primary school students in 24 schools in Phu Wieng district, Khon Kaen province, Thailand. The samples were 1,237 subjects. The data were collected by questionnaires both pretest and posttest then data analyzed by STATA program. The statistics were analyzed descriptive data such as percentage, distribution, arithmetic mean and standard deviation and comparative internal group were used paired sample t-test. After implementation had mean score of knowledge, attitude, perceived, practice for liver fluke prevention higher than before implementation significantly at p<0.001. Students concern that both instruction for liver fluke were useful and increasing good health behavior in addition would be publish for other school further. Health education program for liver fluke preventing behavior by using hand book and VCD in primary school students increasing knowledge, attitude, perception and practice on liver fluke prevention. It should extend to others schools for good health behavior. Keywords: hand book;preventing behavior;liver fluke;Health education program;Effectiveness;VCD;primary school students