Mohammad-Ashraf Ottom, Khalid M.O. Nahar, Izzat Alsmadi, Extraction of Essential Genes Based on Network Attributes, Journal of Engineering and Applied Sciences, Volume 14,Issue 15, 2019, Pages 5183-5189, ISSN 1816-949x, jeasci.2019.5183.5189, (https://makhillpublications.co/view-article.php?doi=jeasci.2019.5183.5189) Abstract: Protein and DNA feature’s extraction represents an interesting research subject for a wide range of relevant applications. In this study, we studied different methods of grouping a large number of genes based on relations with other genes. We used different network metrics such as centrality degree and betweenness to find essential genes. We proposed and developed an algorithm to extract the total and weighted strengths in associating gene’s relations with each other. The results showed that such group related metrics can be used to effectively extract knowledge about genes and their associations with other genes as well as with diseases. Keywords: Genes;genes groups;maximum cliques;genecards;group centrality metrics;network metrics