Jiang Hu, Shaobin Li, Xiu Liu, Yuzhu Luo, Li Zhang, Wei Yan,
Single Nucleotide Polymorphisms of the Calpain 3 (CAPN3) Gene in
Yak,
Agricultural Journal,
Volume 8,Issue 3,
2013,
Pages 119-122,
ISSN 1816-9155,
aj.2013.119.122,
(https://makhillpublications.co/view-article.php?doi=aj.2013.119.122)
Abstract: The Calpain3 (CAPN3) gene, located within the confidence
interval of the Quantitative Trait Loci (QTL) affecting meat tenderness, being
regarded as a candidate gene for meat tenderness in cattle. In this study, SNPs
in exon 23-intron 23 region of the yak CAPN3 was investigated from 1032 yak
with Polymerase Chain Reaction-Single Strand Conformational Polymorphism (PCR-SSCP).
Three Single-Nucleotide Polymorphisms (SNPs), resulting in three novel alleles
were detected in this region, respectively. These variations included one synonymous
in exon 23 and two SNPs in intron 23. Allele C was the most common allele (63.18%)
in all of yak. These SNPs are the first report in yak CAPN3 and also suggest
further analysis is required to explore the relations between variation sites
and meat tenderness.
Keywords: Single Nucleotide Polymorphism (SNP);Calpain 3 (CAPN3) gene;Yak (Bos grunniens);PCR-SSCP;China