Saman  Hosseini, Mir  Behrad Khamesee, 
    Assessment of <i>Helicobacter pylori</i> Eradication Treatment on Platelet Count in Patients with
Immune Thrombocytopenic Purpura,
    International Journal of Tropical Medicine,
    Volume 17,Issue 2,
    2022,
    Pages 20-28,
    ISSN 1816-3319,
    ijtmed.2022.20.28,
    (https://makhillpublications.co/view-article.php?doi=ijtmed.2022.20.28)
    Abstract: The impact of <i>H. pylori</i> eradication on the
platelet count in patients with Immune Thrombocytopenic
Purpura is controversial. In this clinical trial, the effects of
HP eradication on platelet count was assessed and
analyzed. Forty Iranian patients with ITP were assessed in
two groups. One group was treated with amoxicillin,
clarithromycin and omeprazole. The other group received
similar amounts of placebo. The platelet counts were
analyzed before treatment and during the first, second and
third months after treatment. The mean platelet count
before treatment in the intervention and control groups
were, 67.85&times;103 and 69.4&times;103 mm<sup>3</sup>, respectively
(p = 0.82). In the third month after treatment, it was
107.15&times;103 mm<sup>3</sup> in the intervention group and the
71.15&times;103 mm<sup>3</sup> in the control group (p<0.001). Repeated
measures analysis confirmed the positive effect of
<i>H. pylori</i> eradication on platelet count (p = 0.007). In this
study, it was found that <i>H. pylori</i> eradication in patients
with immune thrombocytopenic purpura induced a
dramatic increase in platelets count.
    Keywords: H. pylori;Immune thrombocytopenic purpura;platelet count;eradication