Paul M. Wanjala, Battan M. Khaemba, Alfred I. Luoba,
Prevalence and Intensity of Infection of Intestinal Schistosomiasis and Reinfection after Intervention in Budalangi Endemic Focus of Western Kenya,
International Journal of Tropical Medicine,
Volume 8,Issue 3,
2013,
Pages 71-80,
ISSN 1816-3319,
ijtmed.2013.71.80,
(https://makhillpublications.co/view-article.php?doi=ijtmed.2013.71.80)
Abstract: Human schistosomiasis or bilharziasis is a water borne disease
of man caused by trematodes of the genus Schistosoma and transmitted
by fresh water snails. It is one of the most widespread parasitic infections
being second only to malaria in its socioeconomic and public health importance
in tropical and subtropical areas. Intestinal schistosomiasis is endemic only
in areas with certain physical characteristics and risk factors. A 2 years study
was conducted in the Budalangi endemic focus of Western Kenya to determine prevalence
and intensity of infection and reinfection in the risk population with a view
of instituting a deworming programme in primary schools. Stool samples collected
from 972 school children aged 5-14 years in 18 randomly selected schools were
examined for ova of S. mansoni. A questionnaire was used to obtain demographic
information and to quantify exposure to infested surface waters. The mean prevalence
of infection in all schools (32.1%; range 0.0-65.0%) was significantly higher
in females (58.0%) than in males sampled (42.0%) (χ2; p<0.05).
Intensity of infection was predominantly light with 65.1% of the infected population
harbouring GMEC 1-99 epg. The prevalence of infection significantly varied with
age groups (χ2-test; p<0.05). The 8-11 years age group accounted
for 49.5% of the potential contamination of contact sites by ova of S. mansoni.
The prevalence and intensity of infection significantly dropped (Studentised
t-test; p<0.05) after treatment with praziquantel coupled with training in
primary hygiene. Proximity to the lake shoreline (R2 = 0.89, p<0.05),
contact with lake water (χ2; p<0.05) and specific water-related
activities including swimming (OR = 1.70; 95% CI = 1.03-2.81), fishing (OR =
3.23; 95% CI = 1.70-6.15) and washing clothes in the lake (OR = 2.07; 95% CI
= 1.27-3.38) were all associated with high risks of infection. The studies showed
that there was a continuous low level of transmission of S. mansoni in
the study area among the various exposure groups attributable to inevitable
contact with permanent water bodies which the vector snail used for breeding.
The level of infection in the human population determined in these studies could
be used for planning and implementing combined mass treatment of people who
reside in the study area in order to enhance control of the parasite.
Keywords: Intesinal schistosomiasis;prevalence;intensity;deworming;reinfection