G. Senthilvel  , M. Jegadeesan  , Anoop Austin  , P. Thirugnanasambantham  , E. Mayisvren  , M. Balasubramanian  , N. Narayanan  , S. Viswanathan  , 
    Effect of a Polyherbal Formulation <I>(Diarun plu</I>s) on Streptozotocin Induced Experimental Diabetes,
    International Journal of Tropical Medicine,
    Volume 1,Issue 2,
    2006,
    Pages 88-92,
    ISSN 1816-3319,
    ijtmed.2006.88.92,
    (https://makhillpublications.co/view-article.php?doi=ijtmed.2006.88.92)
    Abstract: <I>Diarun plus </I>was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced
diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500
mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not
significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising
drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be
considered as a therapeutic agent, wherever elevated glycemic status is observed.
    Keywords: Diarun plus;polyherbal;hyperglycemia;diabetes mellitus;streptozotocin