S. Pramoth Chander, Balakrishnan  , 
    Evaluation of Varying Doses of Magnesium as an Adjuvant to Ropivacaine in Supra Clavicular Brachial Plexus Block,
    Research Journal of Medical Sciences,
    Volume 19,Issue 3,
    2025,
    Pages 121-128,
    ISSN 1815-9346,
    makrjms.2025.3.121.128,
    (https://makhillpublications.co/view-article.php?doi=makrjms.2025.3.121.128)
    Abstract: <p style="text-align:justify">Peripheral nerve blockade is one of the components of comprehensive anaesthesia care because of its distinct advantages over central neuraxial blockade and general anaesthesia. Peripheral Nerve Blockade provides more effective analgesia with fewer side effects than opioid and other oral analgesics. Hence, various adjuvants like opioids, clonidine, neostigmine, dexamethasone, midazolam, etc., were added to local anaesthetics in brachial plexus block to achieve quick, dense and prolonged block, but the results are either inconclusive or associated with side effects Magnesium has been used in intravenous, intrathecal, epidural/caudal routes to improve analgesia. After obtaining permission from our institutional ethical committee, written informed consent was taken from all the study subjects. Totally 90 patients were randomly allocated to three equal groups (n=30 in each group) using computer generated random number list. This study is a prospective double‐blinded randomized controlled study. Inclusion Criteria are Both sexes, Aged 18‐60 yrs, belonging to ASA I and II, posted for elective upper limb surgeries in sree Mookambika college. Supra clavicular block is administered at the level of nerve trunk of the brachial plexus. The sole sensory, motor and sympathetic supply of upper limb are conducted by three nerve trunks contained in a very small, compact, easily accessible and relatively superficial area. Magnesium sulphate has been used as an adjuvant with local anaesthetics under neuraxial anaesthesia in both spinal and epidural routes, even with different doses. This study it is concluded that on addition of both 100 mg and 150 mg magnesium sulphate to 0.5% ropivacaine in supra clavicular brachial plexus block significantly prolongs the duration of sensory and motor blockade and significantly reduces the requirement of rescue analgesic in postoperative period but delays the onset time of sensory and motor blockade. But both 100 mg and 150 mg magnesium had similar efficacy of postoperative analgesia.</p>

    Keywords: Ropivacine; supra clavicular block