Abhishek Sing, Vishakha Singh, Neelam Patel, Tanya Mahindra, Thyroid Dysfunction In Women with Menstrual Disorders in the Reproductive Age Group: An Observational Study, Research Journal of Medical Sciences, Volume 17,Issue 1, 2023, Pages 28-31, ISSN 1815-9346, 10.59218\makrjms.2023.28.31, (https://makhillpublications.co/view-article.php?doi=10.59218\makrjms.2023.28.31) Abstract:

Thyroid disorders represent a prevalent category of endocrine disorders on a global scale. Thyroid dysfunction has the potential to interfere with numerous metabolic and physiological processes, including the menstrual cycle. The objective of this investigation was to identify a correlation between thyroid dysfunction and menstrual irregularities among female individuals. The present investigation is a cross‐sectional study comprising a sample of 200 female participants. Women who experience menstrual disorders during their reproductive years. The study examined thyroid dysfunction in females who presented with menstrual irregularities. The evaluation of thyroid function was conducted by measuring the levels of serum free triiodothyronine (T3), free thyroxine (T4) and thyroid stimulating hormone (TSH). The study participants had a mean age of 25.7±6.8 years. The prevalent menstrual disorder among the participants was irregular menstrual cycle, accounting for 72.5% of the cases, followed by amenorrhea at 21.9% and menorrhagia at 5.6%. The age distribution of the patients revealed that the largest proportion (51.1%) fell within the age range of 15 to 24 years, followed by those aged 25‐34 years (36.1%) and those aged 35 to 45 years (12.9%). The average levels of free T3 and T4 were 2.91±1.05 pg mL-1 and 1.42±0.57 ng dL-1, respectively. The mean TSH level was 2.0 mIU L-1 with an interquartile range of 1.0‐4.0. A prevalence of 25.8% (n = 60) was noted among the female population with regards to thyroid dysfunction. The prevalent thyroid dysfunctions in the study population were subclinical hypothyroidism (14.2%, n = 33), subclinical hyperthyroidism (6.9%, n = 16), overt hyperthyroidism (3%, n = 7) and overt hypothyroidism (1.7%, n = 4). The findings of the research indicate that there is a high prevalence of thyroid dysfunction, specifically subclinical hypothyroidism, among women who experience menstrual disorders. Conducting thyroid function screening on patients with menstrual disorders could be beneficial in eliminating thyroid disorders as possible causative factors for menstrual disturbances.

Keywords: Menstrual disorder; thyroid dysfunction; reproductive age