T.O. Oluyo , R.O. Ayeni , A Mathematical Model of Virus Neutralizing Antibody Response, Research Journal of Applied Sciences, Volume 2,Issue 8, 2007, Pages 889-891, ISSN 1815-932x, rjasci.2007.889.891, (https://makhillpublications.co/view-article.php?doi=rjasci.2007.889.891) Abstract: Controlling the spreads of the disease is a primary goal of health administrators. In this study, we examine a mathematical model of virus neutralizing antibody response using a stability of the model based on Perron theorem. It is shown that the spread of the disease can be controlled if the critical parameter , where B* is the scale initial value of B cells and ยต6 is the death rate of the free virus. Keywords: Spread;neutralizing;control;disease;mathematical model;antibody response