Hani A.  Masaadeh, Wail A.  Hayajneh, Isra`a A.  Al Azzam, Ahed J.  Alkhatib, 
    Prevalence of <I>Streptococcus pneumoniae</I> Serotypes (Nasopharyngeal Colonization) in Children in North Jordan: Genotypic and Phenotypic Characteristics,
    Research Journal of Biological Sciences,
    Volume 11,Issue 1,
    2016,
    Pages 23-33,
    ISSN 1815-8846,
    rjbsci.2016.23.33,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2016.23.33)
    Abstract: Nasopharyngeal swabs were collected from children &lt;5 years who attend King Abdullah Teaching Hospital and the emergency room at Princess Rahma Teaching hospital in North Jordan. <I>S. pneumoniae</I> identification was confirmed using colonial morphology, susceptibility to optochin and bile solubility. Sequential multiplex PCR test was used to determine capsular serotypes of <I>S. pneumoniae</I> isolates. 37.8% of children were carriers to capsulated <I>S. pneumoniae</I>. The most prevalent <I>S. pneumoniae</I> serotypes were 6A/B (13.2%), 23F (7%), ST14 (6%), 9V (4.4%), 11A (3.2%), 19F (3%), ST3 (1.8%), ST4 (1.8%), 12F (1.6%), 35B (1.4%), 19A (0.8%), 7F (0.6%). This type of colonization was not statistically related to acute illness. These moderately high colonization rates are expected to help future research to determine streptococcal strains causing invasive disease and subsequently help in making decision regarding the appropriateness of using new conjugate pneumococcal vaccines.
    Keywords: Streptococcus pneumoniae;serotype;nasopharyngeal colonization;children;genotype;phenotype