Bizhan Mahmoudi, Majnoun Sh. Babayev, The Investigation of Genetic Variation in Taleshi Goat Using Microsatellite Markers, Research Journal of Biological Sciences, Volume 4,Issue 6, 2009, Pages 644-646, ISSN 1815-8846, rjbsci.2009.644.646, (https://makhillpublications.co/view-article.php?doi=rjbsci.2009.644.646) Abstract: In this study, the genetic variation in Taleshi goats were investigated using 9 microsatellite markers (LSCV41, LSCV36, TGLA122, MAF64, oarFCB304, oarJMP23, oarAE133, BM121, BM4621) all of nine loci were amplified successfully. The objectives of this study were to assess the genetic variability among Taleshi goat breed. The genetic characterizations of this genetic resource are essential to conservation and breeding programs. Hardy-Weinberg Equilibrium (HWE) had been tested in the level of probability (p<0.005). Blood sample were collected from spreading location of this breed. Genetic variation taking into account all loci had been estimated on the base expected the unbiased average of Heterozygosity (He). Furthermore, other criteria of genetic variation including PIC values and Shanon information index had calculated in this study. This research was shown that microsatellite technique is a useful tool for evaluation of genetic variation among of domesticated animals. Keywords: Taleshi goat;microsatellite markers;genetic variation;polymorphism;heterozygosity;HWE