A. Aladedunye Felix , A. Okorie Domingo , Antioxidant Activity and Chemical Constituents of Pupalia lappacea (L.) Juss, Research Journal of Biological Sciences, Volume 3,Issue 7, 2008, Pages 783-785, ISSN 1815-8846, rjbsci.2008.783.785, (https://makhillpublications.co/view-article.php?doi=rjbsci.2008.783.785) Abstract: Phytochemical analysis of foliage of Pupalia lappacea (L.) Juss (Amaranthaceae) afforded 8 compounds, namely; 1-docosanol, stearic acid, stigmasterol, -sitosterol, N-benzoyl-L-phenylalaninol acetate, -sitosterol-3-O- -D-glucopyranoside, stigmasterol-3-O- -D-glucopyranoside and 20-hydroxyecdysone. The ecdysteroid, 20-hydroxyecdysone, constitutes nearly 0.3% of the dry weight and 13% of the dichloromethane extracts of the plant, making Pupalia lappacea a probable commercial source for this important ecdysteroid. Both the hexane and dichloromethane extracts showed significant antioxidant activity with the dichloromethane exhibiting an IC50 comparable to that of BHT, a synthetic antioxidant. All the isolated compounds are reported for the first time in the genus. Keywords: Pupalia lappacea (L.) Juss. (Amaranthaceae);ecdysteroid;20-hydroxyecdysone;antioxidant activity;saropeptate