A. Aladedunye Felix , A. Okorie Domingo ,
Antioxidant Activity and Chemical Constituents of Pupalia lappacea (L.) Juss,
Research Journal of Biological Sciences,
Volume 3,Issue 7,
2008,
Pages 783-785,
ISSN 1815-8846,
rjbsci.2008.783.785,
(https://makhillpublications.co/view-article.php?doi=rjbsci.2008.783.785)
Abstract: Phytochemical analysis of foliage of Pupalia lappacea (L.) Juss (Amaranthaceae) afforded 8 compounds, namely; 1-docosanol, stearic acid, stigmasterol, -sitosterol, N-benzoyl-L-phenylalaninol acetate, -sitosterol-3-O- -D-glucopyranoside, stigmasterol-3-O- -D-glucopyranoside and 20-hydroxyecdysone. The ecdysteroid, 20-hydroxyecdysone, constitutes nearly 0.3% of the dry weight and 13% of the dichloromethane extracts of the plant, making Pupalia lappacea a probable commercial source for this important ecdysteroid. Both the hexane and dichloromethane extracts showed significant antioxidant activity with the dichloromethane exhibiting an IC50 comparable to that of BHT, a synthetic antioxidant. All the isolated compounds are reported for the first time in the genus.
Keywords: Pupalia lappacea (L.) Juss. (Amaranthaceae);ecdysteroid;20-hydroxyecdysone;antioxidant activity;saropeptate