Owokotomo I. Adekunle  , 
    Biotransformation of Acetylenic Thiophenes Isolated from <I>Tagetes patula</I> (African Marigold),
    Research Journal of Biological Sciences,
    Volume 2,Issue 4,
    2007,
    Pages 424-426,
    ISSN 1815-8846,
    rjbsci.2007.424.426,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2007.424.426)
    Abstract: The biotransformation of four naturally occurring acetylenic thiophenes; 5-(3-buten-l-nyl)-2, 2<SUP>1</SUP>-bithienyl (I), alpha-terthienyl (II); 5-(4-acetoxy-1-butinyl)-2, 2<SUP>1</SUP>-bithienyl (III); and 5-(4-hydroxy-1-butinyl)-2, 2<SUP>1</SUP>-bithienyl (IV) isolated from the root of <I>Tagetes</I> <I>Patula nana</I> (African marigold) by the microflora in fermenting cassava substrate was investigated. One of the thiophenes, 5-(4-acetoxy-1-butinyl)-2, 2<SUP>1</SUP>-bithienyl (III) was successfully hydrolised after 7 days of fermentation.
    Keywords: Biotransformation;tagetes patula;acetylenic thiopheness;microflora;fermentation;cassava root