I.A.A.  Ejima, 
    Comparative Evaluation of the Efficacy of Praziquantel (PZQ) and Niridazole/Ambilhar (N/A) in the Treatment of Urinary Schistosomiasis among School Children Examined in Idah and Ibaji Local Government areas (LGAs) of Kogi State, Nigeria,
    International Journal of Molecular Medicine and Advance Sciences,
    Volume 11,Issue 1,
    2015,
    Pages 1-8,
    ISSN 1813-176x,
    ijmmas.2015.1.8,
    (https://makhillpublications.co/view-article.php?doi=ijmmas.2015.1.8)
    Abstract: The study was carried out among school children in: Government Day Secondary School and Local Government Education Authority (LGEA) Primary School, Ejule-Ojebe in Ibaji Local Government Area (LGA) and LGEA Primary School, Idah in Idah LGA, Nigeria. It was designed to validate the already established protocol of using Praziquantel (PZQ) as a drug of choice in the treatment of schistosomiasis and other helminths. The cure rate procured by PZQ (66.7%) was significantly higher than that of Niridazole/Ambilhar (N/A) (36.0%) (p<0.05). The validation of the efficacy of praziquantel was established in this study when it was observed in one of the subjects examined whose initial egg-count at week zero was 40 eggs/10 mL urine who failed to turn up for treatment (served as a ‘control’) had egg-excretion increased significantly up to 1,420 eggs/10 mL urine in the 20th week post-treatment when re-examined. Generally, the results showed that there was significant difference (p<0.05) in the percentage cure rate in children placed on PZQ-regimen in the three schools surveyed.
    Keywords: Cure rate;efficacy;niridazole/ambilhar;praziquantel;schistosomiasis