Lawrence M. Agius  , 
    Chronic Pain as Integral Dysfunctionality of Body-Self,
    International Journal of Molecular Medicine and Advance Sciences,
    Volume 2,Issue 3,
    2006,
    Pages 330-333,
    ISSN 1813-176x,
    ijmmas.2006.330.333,
    (https://makhillpublications.co/view-article.php?doi=ijmmas.2006.330.333)
    Abstract: Dimensions of the neuromatrix appear to encompass a reality of integral representation of the pain phenomenon beyond the confines of the thalamus and cortex. It might prove significant that template modeling involves not only replication of events that represent receptivity but also a reconstitution of pathways of transfer dynamics borne out by plasticity of synaptic connectivity. Indeed, cortical reconstruction appears only to partly account for a phenomenon of integration that in turn only partly encompasses synaptic transmission. Synaptic connectivity accounts at least in part for a realization phenomenon that reduplicates the pain experience as a persistent evolution of experience. One might recognize dynamics of involution of peripheral somatic and visceral regions in terms of organ dysfunctionality beyond the compass of cortical representation. Indeed, there would evolve a series of representative steps as reproducible processes of integration within the neuromatrix in a manner that strictly redefines such neuromatix in evolutionary terms. It is in the representation of terms of reference of the constitution of the neuromatrix that substantial representation of receptivity further evolves as persistent and chronic pain.
    Keywords: Chronic pain;dysfunctionality;thalams;cortex