Hongxiang  Sun, Shuiqiao  Fu, 
    Immunological Adjuvant Activity of Two Chinese Medicine Prescription Preparations,
    Journal of Animal and Veterinary Advances,
    Volume 12,Issue 10,
    2013,
    Pages 1007-1015,
    ISSN 1680-5593,
    javaa.2013.1007.1015,
    (https://makhillpublications.co/view-article.php?doi=javaa.2013.1007.1015)
    Abstract: The aim of this study was to evaluate and compare adjuvant 
  potential of two widely used Chinese medicine prescription preparations Golden 
  Screen health Capsules (GSC) and Yupingfeng Koufuye (YPF) on immune responses 
  to Ovalbumin (OVA) in mice. Mice were administered orally with GSC or YPF at 
  the different doses for 5 days and then immunized subcutaneously twice with 
  OVA 100 μg alone at 2 weeks intervals. The 2 weeks later, splenocyte proliferation, 
  Natural Killer (NK) cell activity, production of cytokines from splenocytes 
  and serum OVA-specific antibody titers were measured. GSC and YPF significantly 
  not only the serum OVA-specific IgG and IgG1 antibody titers but remarkably 
  enhanced Con A-LPS and OVA-induced splenocyte proliferation and NK cells activities 
  in OVA-immunized mice. The production of cytokine IL-2 from splenocytes and 
  serum OVA-specific IgG2a and IgG2b antibody titers in the immunized mice were 
  also significantly enhanced by YPF. YPF was better than GSC and alum in the 
  quality and strengths to enhance specific cellular and humoral immune responses 
  against OVA in mice with YPF preferred for those situations where mixed Th1/Th2 
  responses are needed.
    Keywords: Golden Screen health Capsules (GSC);Yupingfeng Koufuye (YPF);adjuvant;oral administration;cellular and humoral immune responses