M.  Najiah, A.I.  Zamani, M.  Nadirah, M.A.  Amiza, 
    Evidence of a Heparin-Binding Protein in the Plasma of the Slipper Oyster, <I>Crassostrea iredalei</I>,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 22,
    2012,
    Pages 4147-4155,
    ISSN 1680-5593,
    javaa.2012.4147.4155,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.4147.4155)
    Abstract: Recognition proteins play an important role in the immunodefense 
  system of invertebrates. The haemolymph of the Slipper oyster, <I>Crassostrea 
  iredalei</I>, contains a heparin-binding protein with a molecular weight of 
  35 kDa as determined by SDS-PAGE analysis. The protein was purified using column 
  chromatography. This binding protein possesses a serine protease activity thus 
  it is capable of activating the prophenoloxidase-activating (proPO) system. 
  However, the protein lacks &#946;-1,3-glucanase activity. Using rabbit antiserum 
  against the isolated protein in immunodiffusion and immunoblotting assays it 
  produced a single precipitant and a single band, respectively. However, N-terminal 
  amino acid sequence of BGBP: Threonine-Alanine-Arginine-Asparagine-Glutamic 
  acid-Alanine-Asparagine-Valine was similar to Cavortin (AAT44352) and extracellular 
  superoxide dismutase (AAY60161) from <I>C. gigas</I>.
    Keywords: Heparin-Binding Protein (HBP);Crassostrea iredalei;2D-electrophoresis;proPhenoloxidase-activating (proPO) system;Malaysia