Gong-Zheng  Hu, Hua  Wu, Shan-Mei  Wang, Yu-Shan  Pan, Bao-Guang  Liu, Zhi-Pei  He, 
    Phenotypic Detection and Drug Resistance Analysis of Extended-Spectrum &#946;-Lactamases among <I>Escherichia coli</I> Isolates from Diseased Duck,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 21,
    2012,
    Pages 3870-3875,
    ISSN 1680-5593,
    javaa.2012.3870.3875,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.3870.3875)
    Abstract: Thirty two <I>Escherichia coli</I> isolates recovered from diseased ducks diagnosed with colibacillosis in China between 2010 and 2011 were characterized for detection of Extended-Spectrum &#946;-Lactamases (ESBLs) by phenotypic screening and confirmatory test provided by the Clinical Laboratory Standards Institute and antimicrobial susceptibility profiles via agar disk diffusion and a broth doubling dilution method. Results showed 7 of the 32 <I>E. coli</I> isolates analyzed (21.87%) were found to be ESBL producers. The resistant rates of ESBL producers were &gt;28.6% against third generation cephalosporins and semisynthetic penicillins and as high as 100% against amoxicillin, ampicillin and ceftiofur. All 32 isolates were sensitive to imipenem, meropenem and cefepime and the susceptible rates of all 32 isolates to &#946;-lactam antibiotics in combination with enzyme inhibitors were higher than those of &#946;-lactam antibiotics alone. Therefore, ESBL-producing isolates had multi-drug resistance and enzyme inhibitors can partially solve the drug resistance problem.
    Keywords: Duck;Escherichia coli;Extended-Spectrum Beta-Lactamases (ESBLs);phenotype;antibiotics susceptibility