Xiao-Rong  Zhang, Yinghui  Ling, Lijuan  Wang, Xiaodong  Zhang, Lina  Xu, Jian-Ping  Ding, Yun-Hai  Zhang, Zijun  Zhang, 
    The Correlation Between Goat <I>Cox II</I> Gene Single Nucleotide Polymorphism and Sperm Motility,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 20,
    2012,
    Pages 3677-3681,
    ISSN 1680-5593,
    javaa.2012.3677.3681,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.3677.3681)
    Abstract: This study is about the correlation between <I>COX II</I> 
  gene genetic variation and adult buck sperm motility traits, to provide genetics 
  reference for the goat breeding. In this study, 120 adult male goat semen samples 
  were collected from four populations.<I> COX II</I> gene polymorphism information 
  was rapid screened using DNA pool and sequencing method. Each individual polymorphism 
  of these goats was detected by RFLP. Sequencing results of DNA pool showed a 
  single nucleotide mutation in <I> COX II</I> gene (A&rarr;G). The mutation caused 
  a change of Hind III restriction site. RFLP results showed that the mutation 
  associated with goat sperm traits. The vitality of fresh sperm and frozen sperm 
  from BB-type goats was significantly higher than AA-type. This study provided 
  foundation for establishment relationship between <I> COX II</I> gene SNP and 
  goat sperm motility traits. It could be considered as a reference marker-assisted 
  selection for buck semen quality traits and goat breeding.
    Keywords: Goat;COXII gene;genetic variation;sperm motility;breeding;mutation