Ahmet  Aydin, Gonca  Alak, Esat Mahmut  Kocaman, Muhammed  Atamanalp, 
    Effects of Carboxin on Glutathione-S-Transferase Enzyme Activite in Rainbow Trout (<I>Oncorhynchus mykiss</I>),
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 15,
    2012,
    Pages 2716-2720,
    ISSN 1680-5593,
    javaa.2012.2716.2720,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.2716.2720)
    Abstract: Carboxin is one of the most widely used fungicides in agriculture but information about toxicity on fish is limited. The aim of this study was to determine the effects of exposure to carboxin on the Antioxidant Defense System of rainbow trout (<I>Oncorhynchus mykiss</I>). The fish were exposed to carboxin (3.85 ppm) for 7 days. The antioxidant parameter (Glutathione-S-Transferase (GST)) was measured in fish liver samples. The results indicated that carboxin exposure significantly affected the activity of GST in rainbow trout liver (p&lt;0.01). Thus, it was assumed that carboxin caused oxidative stress in rainbow trout and GST enzyme played a role in protection against carboxin toxicity.
    Keywords: Carboxin;rainbow trout;toxicity;antioxidant enzyme;GST;MDA