Changjun  Li, Xiaolan  Wu, Xiaojuan  Lou, Yajun  Wu, Ang  Li, Haiyan  Wang, 
    Protective Effects of Crude Polysaccharide from <I>Gynostemma pentaphyllum </I>on Swimming Exercise-Induced Oxidative Stress in Rat,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 10,
    2012,
    Pages 1627-1632,
    ISSN 1680-5593,
    javaa.2012.1627.1632,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.1627.1632)
    Abstract: The present study examined the effects of crude Polysaccharide from <I>Gynostemma pentaphyllum</I> (PGP) against oxidative stress induced by swimming exercise. Male rats were administered PGP (50, 100, 200 and 400 mg kg<SUP>-1</SUP>) by gavage every day. After 30 days, swimming exercise of rat was performed in acrylic plastic pool. The results showed that PGP treatment prolonged exhaustive swimming time and improved liver glycogen reserve which suggested that PGP treatment influenced the performance of exhaustive exercise and improved exercise tolerance. Moreover, PGP treatment can promote increases in the activities of Super Oxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GPH-Px) and reduce lipid per-oxidation which suggest that PGP treatment was beneficial in enhancing the antioxidant status and inhibiting oxidative stress induced by exhaustive exercise.
    Keywords: Crude polysaccharide from Gynostemma pentaphyllum;oxidative stress;swimming exercise;rat;SOD;China