Qigai He  , Pin  Chen, Yingyu Liu  , Yang Wang  , Wentao Li  , Dingren Bi  , 
    Plasmid Mediated Streptomycin and Sulfonamide Resistance in <I>Haemophilus parasuis </I>,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 8,
    2012,
    Pages 1106-1109,
    ISSN 1680-5593,
    javaa.2012.1106.1109,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.1106.1109)
    Abstract: Streptomycin and sulfonamide resistance in <I>Haemophilus parasuis </I>is an emerging phenomenon that has not yet been characterized from a molecular perspective. The aim of the present research was to determine the molecular mechanism of <I>Haemophilus parasuis </I>resistant to streptomycin and sulfonamide. One high level streptomycin and sulfonamide-resistant isolate from China was submitted for MIC determination and plasmid extract, then sequencing and annotation. One plasmid extracted from the bacteria strain, designated pHPS-A67 (4.2 kb), contain fifteen open reading frames including streptomycin resistance gene <I>StrA</I>, sulfonamide resistance gene <I>Sul 2</I> and mobilization protein genes <I>Mob A</I>, <I>Mob B</I> and <I>Mob C</I>. This is believed to be the first report of native <I>Haemophilus parasuis</I> contains plasmid which mediated streptomycin and sulfonamide resistance in this microorganism.
    Keywords: Haemophilus parasuis;streptomycin;sulfonamide;plasmid;pig;China