Kaizhou  Xie, Huisheng  Guo, Longfei  Jia, Yuping  Huang, Xing  Xie, Yilin  Yao, Dong  Xu, Xuesheng  Chen, Guojun  Dai, Xiaojie  Zhang, Yingying  Sun, Jinyu  Wang, Zongping  Liu, 
    Residue Depletion of Florfenicol and its Metabolite Florfenicol Amine in Eggs,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 7,
    2012,
    Pages 1012-1017,
    ISSN 1680-5593,
    javaa.2012.1012.1017,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.1012.1017)
    Abstract: Eggs of laying hens were used to study residue depletion of Florfenicol (FF) and its metabolite Florfenicol Amine (FFA) after oral dose (25.0, 50.0 and 100.0 mg kg<SUP>-1</SUP> body weight), once daily for 5 days. The residues were determined by High Performance Liquid Chromatography with Fluorescence Detection (HPLC-FLD). The maximum concentration of FF was all detected at 1 day in the albumen, yolk and whole eggs; the maximum concentration of FFA was detected at 1 day in the albumen and whole eggs, at 3 days in the yolk after cessation of medication. After oral administration of 100.0 mg kg<SUP>-1</SUP>, concentrations of FF and FFA were all below the LODs (1.5 &#956;g kg<SUP>-1</SUP> for FF and 0.5 &#956;g kg<SUP>-1</SUP> for FFA) at 7 days for the albumen, 11 days for yolk and 10 days for whole egg after cessation of medication.
    Keywords: Florfenicol;florfenicol amine;residue depletion;eggs;yolk;yolk