Wu  Tian-Wen, Li-Ting  , Feng-Kai  , Mao-Liu-Liu  , Li  Bi-Chun, Wu  Xin-Sheng, 
    Analysis on the Genetic Variation of <I>KAP3.1</I> and <I>KAP6.1</I> Gene in 6 Rabbit Populations,
    Journal of Animal and Veterinary Advances,
    Volume 10,Issue 7,
    2011,
    Pages 894-899,
    ISSN 1680-5593,
    javaa.2011.894.899,
    (https://makhillpublications.co/view-article.php?doi=javaa.2011.894.899)
    Abstract: Researchers had scanned the complete CDS of rabbit <I>KAP3.1</I> and <I>KAP6.1</I> gene for the 1st time by PCR-SSCP and detected that their homology with mouse, chimpanzee, human, sheep and goat were &gt;80%, suggesting that the two genes among different species kept high conservation in evolution. In this study, three genotypes and two alleles were found at KAP3.1-1 locus having one silent mutation (C91T) and there were two alleles and three genotypes in 5 un-translated region of<I> KAP6.1</I> gene with the A 755 G mutation of the enhancer region. Herein, the distribution of these genotypes in all populations was consistent with the Hardy-Weinberg equilibrium and showed intermediate or low diversity. The result suggested a theoretical reference to the breeding of rabbit wool quality whether <I>KAP3.1</I> and<I> KAP6.1</I> gene could be a molecular marker or not.
    Keywords: Rabbit;KAP3.1 gene;KAP6.1 gene;genetic variation;Hardy-Weinberg equilibrium;China