Yaping  Jin, Yi  Li, Dongning  Bai, Aihua  Wang, Xianjun  Zhao, Xuefeng  Qi, 
    Probiotic Activities of Lab in Endometritis: Probiotic Activities of Three Lactic Acid Bacteria Strains Isolated from Healthy Bovine Cervix: <I>In Vitro</I> Adherence to Immortalized Endometrial Epithelial Cells and Antimicrobial Properties,
    Journal of Animal and Veterinary Advances,
    Volume 10,Issue 4,
    2011,
    Pages 484-488,
    ISSN 1680-5593,
    javaa.2011.484.488,
    (https://makhillpublications.co/view-article.php?doi=javaa.2011.484.488)
    Abstract: The ability of three Lactic Acid Bacteria (LAB), i.e., <I>Lactobacillus acidophilus</I>,<I> Enterococcus faecalis</I> and<I> Enterococcus cecorum</I> that isolated from cervical mucus in health cattle to adhere to immortalized Endometrial Epithelial Cells (EEC) and to affect the adhesion of two main endometritis-associated pathogens, <I>Escherichia coli</I> and<I> Staphylococcus aureus</I> were investigated. All probiotic strains exhibited strong adhesion levels to the cell lines and the adhesion levels of <I>L. acidophilus </I>was significantly higher as compared to that of <I>E. faecalis </I>or <I>E.cecorum </I>(p&lt;0.05). In coculture assays, a significant decrease in the number of adhering pathogens was observed, using either preincubation, postincubation or coincubation of the pathogens with these LAB. <I>L.acidophilus</I> exhibited strong antagonistic activity against <I>E. coli </I>(p&lt;0.01), nevertheless, <I>E. Faecalis</I> and<I> E. cecorum </I>showed strong inhibitory effect on <I>S. aureus </I>(p&lt;0.01). In conclusion, the ability of LAB tested to inhibit the adhesion of endometritis-associated pathogens is highly specific and depends on both the probiotic and pathogen strains.
    Keywords: endometritis-associated pathogen;antimicrobial property;adherence;lactic acid bacteria;Immortalized endometrial epithelial cell;China