Necip  Fazil Kishali, 
    Exercise Effects on Menopause-Induced Changes in Heart of Ovariectomized Rats,
    Journal of Animal and Veterinary Advances,
    Volume 10,Issue 8,
    2011,
    Pages 1073-1079,
    ISSN 1680-5593,
    javaa.2011.1073.1079,
    (https://makhillpublications.co/view-article.php?doi=javaa.2011.1073.1079)
    Abstract: The menopause is characterized by the progressive decrease in estrogenic secretion and associated with bio-psycho and social changes which in turn impairs quality of life. This experiment was conducted to determine if exercise training has a protective role against the deleterious effects of aging in ovariectomized rats. Control rats and ovariectomized rats 12 weeks after surgery were subjected to a 4 weeks treadmill-running program. Subgroups established were young animals, old animals, ovariectomized animals, young exercise-trained animals, old exercise-trained animals and ovariectomized exercise-trained animals. In exercise groups, rats were subjected to treadmill exercise during which time each rat walked on a motor-driven treadmill at 15 m min<SUP>-1</SUP> speed and 15&deg; incline once every 2 days during 10 days for three courses as 5, 10 and 15 min day<SUP>-1</SUP> totally for 30 days. In ovariectomized rat, heart tissue was remarkably dens fibrosis and an increase in necrotic cell density, possibly resulting from myocyte defect. Findings of old exercise-trained animal group more resembled young animal group rather than ovariectomized animal group and ovariectomized exercise-trained animal group.
    Keywords: Exercise;heart;menopause;myocyte;overiectomy;rats;Turkey