Sittisak Khampa , Pala Chaowarat , ungson Singhalert , Ruangyote Pilajun , Metha Wanapat , Supplementation of Yeast Fermented Cassava Chip as a Replacement Concentrate on Rumen Fermentation Efficiency and Digestibility of Nutrients in Heifer, Journal of Animal and Veterinary Advances, Volume 8,Issue 6, 2009, Pages 1091-1095, ISSN 1680-5593, javaa.2009.1091.1095, (https://makhillpublications.co/view-article.php?doi=javaa.2009.1091.1095) Abstract: Ten, 1 year old of dairy heifers with initial body weight of 150±10 kg were randomly divided into 2 groups and received concentrate at 14% CP (T1) and Yeast Fermented Cassava Chip (YFCC) (T2). The cows were offered the treatment concentrate at 1% BW and urea-treated rice straw was fed ad libitum. Means were compared using t-test. All animals were kept in individual pens and received free access to water. The results have revealed that replacement of YFCC on feed intake was non-significantly different, while Average Daily Gain (ADG) and digestibility of nutrients were higher (p<0.05) in heifer fed YFCC (T2) treatments than received concentrate at 14% CP (T1) (254.3 and 219.4 g day-1). In addition, the ruminal pH, ammonia-nitrogen and blood urea nitrogen concentration were significantly different (p<0.05). The concentration of volatile fatty acid was significantly different especially the concentration of propionic acid was slightly higher in heifer receiving T2 than T1. Supplementation of YFCC (T2) could improve population of bacteria and fungal zoospore, but decreased populations of Holotrich and Entodiniomorph protozoa in rumen (p<0.05). The results indicate that supplementation of Yeast Fermented Cassava Chip (YFCC) as a replacement concentrate at 14% CP could improve rumen fermentation efficiency and digestibility of nutrients in dairy heifers. Keywords: Saccharomyces cerevisae;cassava chip;rumen fermentation;heifer;Yeast;digestibility