Mehdi Nayebpor , Parviz Farhomand , Ali Hashemi , Effects of Different Levels of Direct Fed Microbial (Primalac) on Growth Performance and Humoral Immune Response in Broiler Chickens, Journal of Animal and Veterinary Advances, Volume 6,Issue 11, 2007, Pages 1308-1313, ISSN 1680-5593, javaa.2007.1308.1313, (https://makhillpublications.co/view-article.php?doi=javaa.2007.1308.1313) Abstract: Probiotics are claimed to have beneficial effects on health. The production parameters, including were monitored weekly during a 6-wk trial. Body weight was affected by dietary treatments in 21, 28 and 42 days of age (p< 0.05). The BW in the 0.1% DFM treatment was significantly (p< 0.05) higher than 0.15% DFM and control in 28 and 42 days. Body weight gain in probiotic treatments was significantly more than control treatment (p< 0.05). Moreover, body weight gains in 0.1% DFM were higher than 0.15% DFM treatment (p< 0.05). Feed intake in control treatment was significantly higher than (p>0.05) 0.1 or 0.15% DFM treatments. Feed conversion ratio in 0.1 and 0.15% DFM treatments was significantly (p< 0.05) better than control treatment. The 0.1% DFM and control treatments have lowest and highest FCR, respectively. The antibody titer against IBDV in 0.1 and 0.15% DFM treatments were significantly (p< 0.01) more than control treatment but no significant difference among 0.1 and 0.15% treatments. It is concluded that dietary supplementation of DFM probiotic improved body weight, body weight gain and feed conversation ratio and enhanced humoral immune response. Keywords: Probiotic;performance;humoral immune response;broiler chickens