M.E. Al-Bowait  , S.E.M. Barakat  , M.H. Al-Nazawi  , M.E. Barri  , A.M. Homeida  , 
    Effects of <I>Convolvulus arvensis</I> (Binweed) on the Activity of Drug Metabolizing Enzymes in Liver of Rats,
    Journal of Animal and Veterinary Advances,
    Volume 5,Issue 9,
    2006,
    Pages 729-731,
    ISSN 1680-5593,
    javaa.2006.729.731,
    (https://makhillpublications.co/view-article.php?doi=javaa.2006.729.731)
    Abstract: The effects of feeding <I>convulvulus arvensis</I> (binweed) at 0.5 and 1g/rat were investigated. Binweed produced no clinical effects or gross lesions in rats. The plant caused decreased concentration of protein in liver homogenate and inhibited the activity of phase-1 but not phase-2 drug metabolizing enzymes. In view of binweed modulating effects on drug metabolizing enzymes, consumption of binweed by human and animal should be prohibited.
    Keywords: Convulvulus arvensis;liver;drug metabolizing enzymes;rats