TY  - JOUR
T1  - Oxidative Stress Vis a Vis Gatsrointestinal Parasitism and Pneumonia in Marwari Goat
AU - Pilania, P.K. AU - Solanki, S. AU - Mohammed, N. AU - Asopa, S. AU - Maan, R. AU - Joshi, A. AU - Sankhala, L.N. AU - Mathur, M. AU - Thori, M.K. AU - Gaur, J.S. AU - Meena, A. AU - Kataria, N. 
JO  - Veterinary Research
VL  - 6
IS  - 3
SP  - 54
EP  - 57
PY  - 2013
DA  - 2001/08/19
SN  - 1993-5412
DO  - vr.2013.54.57
UR  - https://makhillpublications.co/view-article.php?doi=vr.2013.54.57
KW  - Goat
KW  -gastrointestinal parasitism
KW  -erythrocytes
KW  -CAT
KW  -SOD
KW  -pneumonia
AB  - An investigation was carried out to assess oxidative stress in goats of Marwari breed affected from gastrointestinal parasitism and pneumonia belonging to farmers’ stock of arid tract of Rajasthan State, India. The animals were grouped into healthy and affected. All the blood samples were collected in sterile tubes with anticoagulants for erythrocyte separation and determination of erythrocytic Catalase (CAT) and Superoxide Dismutase (SOD) as biomarkers of oxidative stress. Activities of both the enzymes were significantly (p≤0.05) higher in affected animals in comparison to healthy lot. Erythrocytic catalase activity was 2.37 times higher in goats having gastrointestinal parasitism and 3.06 times higher in goats affected with pneumonia. Erythrocytic superoxide dismutase activity was 4.77 times higher in goats having gastrointestinal parasitism and 6.40 times higher in goats affected with pneumonia. It was observed that goats affected with pneumonia showed higher magnitude of enzyme activities in comparison to those having gastrointestinal parasites. Magnitude of change was greater in SOD activities than CAT activities. It can be concluded that gastrointestinal parasites and pneumonia served to produce oxidative stress in the goat. Catalase and superoxide dismutase are considered as potent biomarkers of oxidative stress. They are also named as antioxidant enzymes. Increased activities of both these enzymes signified the presence of oxidative stress in order to combat excessive production of free radicals. Antioxidant supplementation is recommended in cases affected with conditions like parasites and pneumonia to protect the animals from oxidative stress and ensuing damage to cellular machinery.
ER  -