TY - JOUR T1 - Acute Toxicity Assessment on Biochemical and Histopathological Alterations of Bleaching Powder-Exposed Fresh Water Fish Labeo rohita AU - Sinha, Sangeeta AU - Aswale, Manisha AU - Ghongade, Rohini AU - Singh Arora, Manjit JO - Journal of Fisheries International VL - 14 IS - 4 SP - 23 EP - 31 PY - 2019 DA - 2001/08/19 SN - 1817-3381 DO - jfish.2019.23.31 UR - https://makhillpublications.co/view-article.php?doi=jfish.2019.23.31 KW - Bleaching powder KW -sub-lethal toxicity KW -antioxidant enzymes KW -histopathology KW -environment AB - Bleaching power (Calcium hypochlorite) is commercially used as a laundry detergent and the water used for such process goes into the aquatic environment such as water resources. Quality of the water can been indicated by the fishes living in that environment. In the present study, the freshwater fish, Labeo rohita fingerlings were exposed to sub-lethal concentration of bleaching powder for 24, 48, 72 and 96 h. Significant changes were recorded in various enzyme activities, i.e., cytotoxicity marker enzyme (LDH), anti-oxidative enzymes Catalase (CAT), Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx) and Glutathione Reductase (GR) of the bleaching powder treated liver and gill tissues. Lipid peroxides were also significantly increased in liver and gills tissues exposed to bleaching powder. The histological examination of the gills of Labeo rohita revealed the deterioration of bronchial, fusion of secondary gill lamellae secondary gill lamellar epithelium due to bleaching powder. The result showed that acute bleaching powder toxicity severely affects the normal behavior and vital organs which is deleterious for the exposed fish. ER -