TY - JOUR T1 - Mechanism in Antibacterial Activity of Medicinal plant against Candida albicans AU - Park, Jeong-Sook AU - Kyung Park, Mi AU - Lee, Jae-Hyeok JO - Journal of Engineering and Applied Sciences VL - 13 IS - 2 SP - 372 EP - 375 PY - 2018 DA - 2001/08/19 SN - 1816-949x DO - jeasci.2018.372.375 UR - https://makhillpublications.co/view-article.php?doi=jeasci.2018.372.375 KW - Candida albicans KW -disc diffusion method KW -medicinal plant KW -Artemisia apiacea Hance KW -Ulmus macrocarpa Hance (bark) KW -activity AB - The purpose of this study is to determine the mechanism in antibacterial activity of medicinal plant against Candida albicans. In order to best anti-Candida albicans effects for nine kinds of medicinal plant, Artemisia apiacea Hance, Artemisia annua, Brassica oleracea L., Coptis chinensis, Pogostemon cablin Bentham, Loranthus chinensis Danser, Ulmus macrocarpa Hance (bark). Medicinal plant ethanol extracts were examined by disc diffusion method for anti-Candida albicans activity and used fluconazol (50 mg/mL), 99% ethanol as a positive controls. We measured the area of clear zone and evaluated that the larger size of the area was more effectives against Candida albicans. The result of this study, Artemisia apiacea Hance value was highest as 38.2 mm and next Ulmus macrocarpa Hance (bark) 32.8 mm. This result is a result which is equivalent to about 97% when compared to 39.1 mm of the fluconazol (50 mg/mL) positive control. The present results, along with the observation, suggested that Artemisia apiacea Hance and Ulmus macrocarpa Hance (bark) extracts could be anti-Candida albicans agents to cause the infection candidiasis in humans. ER -