TY - JOUR T1 - Toxicity of 2,4-Dichlorophenoxyacetic Acid on African Mud Fish Clarias gariepinus (Teugals) AU - Shallangwa, Sani Mallum JO - Agricultural Journal VL - 6 IS - 4 SP - 177 EP - 180 PY - 2011 DA - 2001/08/19 SN - 1816-9155 DO - aj.2011.177.180 UR - https://makhillpublications.co/view-article.php?doi=aj.2011.177.180 KW - adductor muscles KW -perilamellae fibrosis KW -lamellae KW -Clarias gariepinus KW -toxicity KW -2 KW -4-D KW -Nigeria AB - The acute and sub-lethal toxicity of a herbicide 2,4-Dicholorophenoxyacetic acid (2,4-D) to juveniles of Clarias gariepinus (Teugels) of mean weight of 26.62±1.25 g and standard length of 14.83±0.04 cm were investigated under laboratory condition. In 96 h, LC50 was 86 mg L-1. The toxicant led to initial increase in the opercular ventilation rate which then decreased below the status quo by the end of the 96 h. Restlessness, immobilisation, loss of balance and air gulping were commonly observed before death during the acute bioassay. Exposed cells of the fish gill had coagulation necrosis of the lamellae, perilamellae fibrosis and inflammations. In addition, dose-dependent necrosis of adductor muscles was observed at the highest acute concentration (86 mg L-1). ER -