TY  - JOUR
T1  - Assessment of <i>Helicobacter pylori</i> Eradication Treatment on Platelet Count in Patients with
Immune Thrombocytopenic Purpura
AU - Hosseini, Saman AU - Behrad Khamesee, Mir 
JO  - International Journal of Tropical Medicine
VL  - 17
IS  - 2
SP  - 20
EP  - 28
PY  - 2022
DA  - 2001/08/19
SN  - 1816-3319
DO  - ijtmed.2022.20.28
UR  - https://makhillpublications.co/view-article.php?doi=ijtmed.2022.20.28
KW  - H. pylori
KW  -Immune thrombocytopenic purpura
KW  -platelet count
KW  -eradication
AB  - The impact of <i>H. pylori</i> eradication on the
platelet count in patients with Immune Thrombocytopenic
Purpura is controversial. In this clinical trial, the effects of
HP eradication on platelet count was assessed and
analyzed. Forty Iranian patients with ITP were assessed in
two groups. One group was treated with amoxicillin,
clarithromycin and omeprazole. The other group received
similar amounts of placebo. The platelet counts were
analyzed before treatment and during the first, second and
third months after treatment. The mean platelet count
before treatment in the intervention and control groups
were, 67.85&times;103 and 69.4&times;103 mm<sup>3</sup>, respectively
(p = 0.82). In the third month after treatment, it was
107.15&times;103 mm<sup>3</sup> in the intervention group and the
71.15&times;103 mm<sup>3</sup> in the control group (p<0.001). Repeated
measures analysis confirmed the positive effect of
<i>H. pylori</i> eradication on platelet count (p = 0.007). In this
study, it was found that <i>H. pylori</i> eradication in patients
with immune thrombocytopenic purpura induced a
dramatic increase in platelets count.
ER  -